Michelangelo, Sistine Chapel, Vatican this shows both the ceiling and the last judgment. The ceiling is a beautiful work of art with great detail. The last judgement even has more detail and it was done 29 years after the ceiling.
Florence - Sunset over Arno by Giuseppe Torre :( I miss it SO MUCH. And I must get back here someday so I can get to the top of Il Duomo, and watch the sunset on the Arno from the top of San Michaelangelo.