Carbamazepine (CBZ) (Tegretol) is an anticonvulsant and mood-stabilizing drug used for epilepsy and bipolar disorder, as well as trigeminal neuralgia. It is also used off-label for a variety of indications, including ADHD, schizophrenia, phantom limb syndrome, complex regional pain syndrome, paroxysmal extreme pain disorder, neuromyotonia, intermittent explosive disorder, borderline personality disorder, Myotonia congenita and post-traumatic stress disorder.
The atypical antipsychotics (AAP) (also known as second generation antipsychotics) are a group of antipsychotic tranquilizing drugs used to treat psychiatric conditions. No extrapyramidal side effects. AAP cause weight gain & diabetes.
Figure 6 from FTY720 Story. Its Discovery and the Following Accelerated Development of Sphingosine 1-Phosphate Receptor Agonists as Immunomodulators Based on Reverse Pharmacology Published in Perspectives in Medicinal Chemistry
The combination oxycodone/paracetamol (North American trade name Percocet, generic endocet) is a narcotic pain reliever used to treat moderate to severe acute (short-term) pain. Oxycodone is an analgesic medication synthesized from poppy-derived thebaine. Paracetamol (acetaminophen), chemically named N-acetyl-p-aminophenol, is an analgesic and antipyretic; it is not generally classified as an NSAID because it exhibits only weak anti-inflammatory activity.
Granisetron is a serotonin 5-HT3 receptor antagonist used as an antiemetic to treat nausea and vomiting following chemotherapy. Its main effect is to reduce the activity of the vagus nerve, which is a nerve that activates the vomiting center in the medulla oblongata. It does not have much effect on vomiting due to motion sickness. This drug does not have any effect on dopamine receptors or muscarinic receptors.